Chemical agents or substances that can prevent blood clotting are called anticoagulants or anticoagulants, such as natural anticoagulants (heparin, hirudin, etc.), Ca2+ chelating agents (sodium citrate, potassium fluoride). Commonly used anticoagulants include heparin, ethylenediaminetetraacetate (EDTA salt), citrate, and oxalate. In actual applications, they must be selected according to different needs to obtain the desired effect. Below, Desheng sorted out their application characteristics as follows:
- Heparin
Heparin is the anticoagulant of choice for blood chemical composition testing. Heparin is a kind of mucopolysaccharide containing sulfuric acid groups, with an average molecular mass of 15,000 in the dispersed phase. - Ethylenediaminetetraacetate (EDTA salt)
EDTA can combine with Ca2+ in the blood to form a chelate, the coagulation process is blocked, and the blood cannot coagulate. EDTA salts include potassium, sodium, and lithium salts. - Citrate
Citrate is mainly sodium citrate, and its anticoagulation principle is to combine with Ca2+ in the blood to form a chelate, so that Ca2+ loses its clotting function and the clotting process is blocked, thereby preventing blood clotting. Sodium citrate has two crystals: Na3C6H5O7·2H2O and 2Na3C6H5O7·11H2O. The former is usually used to make a 3.8% or 3.2% aqueous solution and mix with blood in a volume of 1:9.
Four, oxalate
Oxalate is also a commonly used anticoagulant.
Desheng is an established manufacturer of blood collection tube additives, and has formed independent intellectual property rights and professional production and R&D capabilities in blood collection tube additives. It has provided products and raw material solutions for more than 100 domestic and foreign manufacturers. Blood specimen anticoagulation products include heparin sodium, heparin lithium, trisodium citrate, dipotassium EDTA, EDTA tripotassium, potassium oxalate, etc.; blood specimen procoagulant products include blood coagulation powder, blood coagulant, etc.; blood specimens The materials used in the pre-treatment include separating glue and siliconizing agent. A variety of raw materials are available for you to choose. If you need, please click on the official website to consult our professional customer service.
