Follistatin 344 Description :
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Follistatin 344 is an investigational protein therapeutic that builds muscle and increases strength by inhibiting molecules that bind to and signal through a cell surface receptor called Activin Receptor Type IIB (ActRIIB).
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Follistatin 344 is a recombinant fusion protein that is produced by joining a portion of the human ActRIIB receptor to a portion of a human antibody.
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Follistatin 344 is intended for research purpose only. ACE-031 should not be used for human consumption,diagnostic, therapeutic procedures, agricultural and veterinary purposes.ACE-031 is a soluble fusion protein that has been shown to increase muscle mass and strength in research studies.
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Follistatin 344 is being studied as a treatment for metabolic diseases, renal neoplasms of childhood, cardiovascular anomalies, age-related muscle loss, and cancer treatment related muscle loss and neuromuscular diseases.
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Follistatin 344 is a biologic therapeutic, based on activin receptor type IIB (ActRIIB). The molecule inhibits signaling via the ActRIIB receptor binding and increase muscle mass and strength. ACE-031 is a recombinant fusion protein that is artificially synthesized by fusion of standard antibody and a portion of ActRIIB receptor. The recombinant fusion protein eliminates myostatin and other biomolecules that limit muscle strength or growth.
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Follistatin 344 belongs to class of proteins of TGF-beta super family that regulate muscle growth. ACE-031 acts on the molecular switches of these molecules and promote muscle growth. In experimental studies,
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Follistatin 344 promotes muscle growth and inhibits ActRIIB receptor signaling. In pre-clinical studies, administration of ACE-031 for two weeks increased skeletal muscle density, decreased leptin levels, and increased adiponectin.
Why use FOLLISTATIN-344 ?
Follistatin-344 significantly increases muscle growth and muscle strength (by blocking the Moystatin activity) - it promotes hyperplasia (growth of new muscle cells) as well as active hypertrophy (increase in cell size).
Follistatin-344 exhibits a potent anabolic activity (yet without concomitant androgenic activity). Taking Follistatin-344 results in muscular
hyperplasia (growth of new muscle fibres) and active hypertrophy (increase in size of existing muscle fibres)
Follistatin-344 has a strong ability to keep sportsmen in shape and maintain their muscle mass even when they stopped exercising
Follistatin-344 significantly increases performance
Follistatin-344 exhibits a potent anti-aging effect, with a significant impact on rejuvenation of all body tissues
Follistatin-344 promotes body´s fat burning
The recommended dosing of Follistatin-344:
Follistatin-344 should be taken in a dose of 100 to 200 mcg once per day, for the period of 10-20 days.